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KPV is a synthetic tripeptide (Lys-Pro-Val) from positions 11 to 13 of alpha-MSH (342.43 g/mol)

Almost the entire evidence base traces back to one Russian research program from the 1990s and 2000s

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(NOTE: The results were replicated in a separate study using a different NNMT inhibitor, also observing the normalization of tolerance to glucose and increased insulin sensitivity) Already, were seeing some strong interest in using 5-Amino 1MQ to treat obesity and other metabolic diseases in US veterans